Will it run? / Qwen2.5-VL 72B / Ryzen AI Max+ 395 mini PC (128GB)

Can the Ryzen AI Max+ 395 mini PC (128GB) run Qwen2.5-VL 72B?

Too slow to enjoy Yes, at about 3.7 tokens/sec (estimated). It technically runs, but slowly enough to be frustrating.

3.7estimated tokens/sec
50.5 GBmemory needed
96 GBavailable to the model
256 GB/smemory bandwidth
ollama run qwen2.5vl:72b

Check the Ryzen AI Max+ 395 mini PC (128GB) price →

How we got this number

Each generated token reads the whole model from memory once: 49 GB. The Ryzen AI Max+ 395 mini PC (128GB) moves 256 GB/s, so the ceiling is 5.2 tokens/sec. Real machines reach a fraction of that ceiling; we use 70%, an assumption until we get measured runs for this kind of machine. Send us your real numbers and we'll replace the estimate.

Faster machines for Qwen2.5-VL 72B

Mac Studio M5 Ultra (96GB)20 tok/s$5,499Check price →
Mac Studio M5 Ultra (256GB)20 tok/s$9,499Check price →
Mac Studio M5 Max (40-core GPU, 64GB)6.0 tok/s$3,799Check price →
NVIDIA DGX Spark (128GB)3.9 tok/sCheck price →

Other models on the Ryzen AI Max+ 395 mini PC (128GB)

Qwen 3 30B (A3B)Fast52 tok/s
Qwen3 Coder 30B (A3B)Fast52 tok/s
Qwen 3-VL 30B (A3B)Fast50 tok/s
Qwen3.5 35B (A3B)Fast47 tok/s
Qwen3.6 35B (A3B)Fast47 tok/s
gpt-oss 20BFast44 tok/s