Will it run? / Qwen2.5 72B / Mac Studio M5 Ultra (256GB)

Can the Mac Studio M5 Ultra (256GB) run Qwen2.5 72B?

Fast Yes, at about 21 tokens/sec (estimated). Replies stream faster than you can read.

21estimated tokens/sec
48.5 GBmemory needed
192 GBavailable to the model
1228.8 GB/smemory bandwidth
ollama run qwen2.5:72b

Check the Mac Studio M5 Ultra (256GB) price →

How we got this number

Each generated token reads the whole model from memory once: 47 GB. The Mac Studio M5 Ultra (256GB) moves 1228.8 GB/s, so the ceiling is 26 tokens/sec. Real machines reach a fraction of that ceiling; we use 80%, calibrated against a measured Mac run. Send us your real numbers and we'll replace the estimate.

Faster machines for Qwen2.5 72B

Mac Studio M5 Ultra (96GB)21 tok/s$5,499Check price →
Mac Studio M5 Max (40-core GPU, 64GB)6.3 tok/s$3,799Check price →
NVIDIA DGX Spark (128GB)4.1 tok/sCheck price →
Ryzen AI Max+ 395 mini PC (128GB)3.8 tok/sCheck price →

Other models on the Mac Studio M5 Ultra (256GB)

Nemotron 3.5 lightning 30B (A3B)Fast120+ tok/s
Qwen 3 30B (A3B)Fast120+ tok/s
Gemma 4 26B (A4B)Fast120+ tok/s
Qwen3.5 35B (A3B)Fast120+ tok/s
gpt-oss 20BFast120+ tok/s
gpt-oss 120BFast120+ tok/s